Article
DD genotype of the angiotensin I-converting enzyme gene is a risk factor for early onset of essential hypertension in Japanese patients.
The Journal of laboratory and clinical medicine - 1 Jun 1998
Nakano Y, Oshima T, Hiraga H, Matsuura H, Kajiyama G, Kambe M
Abstract excerpt
Although angiotensin-converting enzyme (ACE) plays an important role in blood pressure regulation, no relationship between the insertion/deletion (I/D) polymorphism of the ACE gene and essential hypertension has been observed. However, as the pathogenesis and genetic background of essential hypertension are heterogeneous, we investigated whether the ACE gene is a marker of subgroups of patients with essential...
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