Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Temperature-programmed capillary electrophoresis for the analysis of high-melting point mutants in thalassemias.

Electrophoresis - 1 May 1997

Gelfi C, Righetti P G, Travi M, Fattore S

Abstract excerpt

The behavior of different sieving polymers for unambiguous determination of point mutations in genomic DNA, based on electrophoresis in thin capillaries, is evaluated. High melters from thalassemia patients are separated by exploiting the principle of denaturing gradient gel electrophoresis, in fact, of its variant utilizing temperature gradients (TGGE), along the migration path, encompassing the melting points...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to beta-Thalassemia
Share to DNA
Share to DNA Mutational Analysis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Electrophoresis, Capillary

Share to Globins

Share to Mutation

Share to Nucleic Acid Denaturation

Share to Temperature

Source

Identifiers

PMID: 9194597
DOI: 10.1002/elps.1150180511

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Temperature-programmed capillary electrophoresis for the analysis of high-melting point mutants in thalassemias.PMID 9194597Read ↗

Capillary electrophoresis of DNA for molecular diagnostics: an update.Semantic proximity Read ↗

Validation of double gradient denaturing gradient gel electrophoresis through multigenic retrospective analysis.Semantic proximity Read ↗

Approach to analysis of single nucleotide polymorphisms by automated constant denaturant capillary electrophoresis.Semantic proximity Read ↗

Rapid heteroduplex analysis by capillary electrophoresis.Semantic proximity Read ↗

Evaluation of sieving matrices used to separate alleles by cycling temperature capillary electrophoresis.Semantic proximity Read ↗

Detection of mutations by flow cytometric melting point analysis of PCR products.Semantic proximity Read ↗

Contribution of the TA repeats on melting temperature (T(m)) in a double strand DNA: comparison of two methods and implications in molecular diagnostics.Semantic proximity Read ↗

Identification of in vivo mutations in exon 5 of the human HPRT gene in a set of pooled T-cell mutants by constant denaturant capillary electrophoresis (CDCE).Semantic proximity Read ↗

Capillary electrophoresis of proteins and nucleic acids.Semantic proximity Read ↗

Detection of neutral and charged mutations in alpha- and beta-human globin chains by capillary zone electrophoresis in isoelectric, acidic buffers.Semantic proximity Read ↗

Temperature gradient gel electrophoresis: rapid detection of alpha-1-antitrypsin deficiency carriers.Semantic proximity Read ↗

Detection of mutations in exon 8 of TP53 by temperature gradient 96-capillary array electrophoresis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.