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Article

Contribution of the TA repeats on melting temperature (T(m)) in a double strand DNA: comparison of two methods and implications in molecular diagnostics.

Clinical biochemistry - 1 Jun 2011

Minucci Angelo, Mello Enrica, Tripodi Domenico, Zuppi Cecilia, Capoluongo Ettore

Abstract excerpt

The present paper is aimed to discuss and revise a not recent molecular laboratory protocol describing the behavior of UGT1A1 gene melting curves. Since some problems in the standardization of this already published molecular protocol were found, we tried to improve this method in order to correctly set up the amplification and melting profile steps. Under our standardized conditions, we were able to perfectly...

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PMID: 21402062
DOI: 10.1016/j.clinbiochem.2011.03.027

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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