Article
Formation of intracellular particles by hepatitis B virus large surface protein.
Journal of virology - 1 Jul 1997
Xu Z, Bruss V, Yen T S
Abstract excerpt
Hepatitis B virus small surface protein is synthesized as a transmembrane protein of the rough endoplasmic reticulum (RER) and then buds into the lumen in the form of subviral particles that are secreted. The closely related large surface protein is also targeted to the RER but is retained in a pre-Golgi compartment and cannot be secreted. It has been assumed that the large surface protein remains as a...
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