Formation of intracellular particles by hepatitis B virus large surface protein.

doi:10.1128/JVI.71.7.5487-5494.1997

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Article

Formation of intracellular particles by hepatitis B virus large surface protein.

Journal of virology - 1 Jul 1997

Xu Z, Bruss V, Yen T S

Abstract excerpt

Hepatitis B virus small surface protein is synthesized as a transmembrane protein of the rough endoplasmic reticulum (RER) and then buds into the lumen in the form of subviral particles that are secreted. The closely related large surface protein is also targeted to the RER but is retained in a p...

Topics

Calcium
Calcium-Binding Proteins
Calnexin
Cell Fractionation
Endoplasmic Reticulum, Rough
Humans
Intracellular Membranes
Molecular Chaperones
Mutation
Recombinant Fusion Proteins
Tumor Cells, Cultured
Viral Envelope Proteins
Virion

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