Article
The Vif and Gag proteins of human immunodeficiency virus type 1 colocalize in infected human T cells
1 Jul 1997
Abstract excerpt
The Vif protein of human immunodeficiency virus type 1 (HIV-1) and other lentiviruses is required for efficient replication in primary cells and certain immortalized cell lines in vitro and, in all likelihood, for the establishment of pathogenic infections in vivo. Current hypotheses concerning Vif's mechanism of action posit that it operates in virus-expressing cells during virion assembly, budding, or...
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