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Highly Purified Human Immunodeficiency Virus Type 1 Reveals a Virtual Absence of Vif in Virions

1 Feb 1999

Abstract excerpt

The vif gene of human immunodeficiency virus type 1 (HIV-1) is essential for the productive infection of primary blood-derived lymphocytes, macrophages, and certain human T-cell lines. It has been shown that Vif is associated with HIV-1 virions purified by sucrose density-equilibrium gradient analysis. However, the specificity of Vif incorporation into virions has not been determined. Moreover, recent studies...

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Identifiers

PMID: 9882352
DOI: 10.1128/jvi.73.2.1460-1467.1999

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Related research

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Research trail→

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Highly Purified Human Immunodeficiency Virus Type 1 Reveals a Virtual Absence of Vif in VirionsPMID 9882352Read ↗

Comprehensive Investigation of the Molecular Defect in vif -Deficient Human Immunodeficiency Virus Type 1 VirionsSemantic proximity Read ↗

Characterization of human immunodeficiency virus type 1 Vif particle incorporationSemantic proximity Read ↗

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Human Immunodeficiency Virus Type 1 Vif Protein Is an Integral Component of an mRNP Complex of Viral RNA and Could Be Involved in the Viral RNA Folding and Packaging ProcessSemantic proximity Read ↗

Aberrant Gag protein composition of a human immunodeficiency virus type 1 vif mutant produced in primary lymphocytes.Semantic proximity Read ↗

The Vif and Gag proteins of human immunodeficiency virus type 1 colocalize in infected human T cellsSemantic proximity Read ↗

Association of Nef with the Human Immunodeficiency Virus Type 1 CoreSemantic proximity Read ↗

Vif-deficient HIV reverse transcription complexes (RTCs) are subject to structural changes and mutation of RTC-associated reverse transcription products.Semantic proximity Read ↗

Nef from human immunodeficiency virus type 1(F12) inhibits viral production and infectivity.Semantic proximity Read ↗

Human immunodeficiency virus type 1 Vif is efficiently packaged into virions during productive but not chronic infection.Semantic proximity Read ↗

The human immunodeficiency virus type 1 Vif protein modulates the postpenetration stability of viral nucleoprotein complexesSemantic proximity Read ↗

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