Article
Nuclear localization of Semliki Forest virus-specific nonstructural protein nsP2.
Journal of virology - 1 May 1990
Peränen J, Rikkonen M, Liljeström P, Kääriäinen L
Abstract excerpt
About 50% of Semliki Forest virus-specific nonstructural protein nsP2 is associated with the nuclear fraction in virus-infected BHK cells. Transport into the nucleus must be specific, since only trace amounts of nsP3 and nsP4 and about 13% of nsP1, all derived from the same polyprotein, were found in the nucleus. Subfractionation of [35S]methionine-labeled Semliki Forest virus-infected cells showed that 80 to 90%...
Topics
- Animals
- Base Sequence
- Capsid
- Cell Line
- Cell Nucleus
- Cell Transformation, Viral
- Fluorescent Antibody Technique
- Molecular Sequence Data
- Mutation
- Oligonucleotide Probes
- Plasmids
