Article
Normal and atypical butyrylcholinesterases in placental development, function, and malfunction.
Cellular and molecular neurobiology - 1 Jun 1997
Sternfeld M, Rachmilewitz J, Loewenstein-Lichtenstein Y, Andres C, Timberg R, Ben-Ari S, Glick C, Soreq H, Zakut H
Abstract excerpt
1. In utero exposure to poisons and drugs (e.g., anticholinesterases, cocaine) is frequently associated with spontaneous absorption and placental malfunction. The major protein interacting with these compounds is butyrylcholinesterase (BuChE), which attenuates the effects of such xenobiotics by their hydrolysis or sequestration. Therefore, we studied BuChE expression during placental development. 2. RT-PCR...
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