Article
Chinese hamster ovary cell mutants affecting cholesterol metabolism.
Current opinion in lipidology - 1 Apr 1997
Chang T Y, Hasan M T, Chin J, Chang C C, Spillane D M, Chen J
Abstract excerpt
The approach of somatic cell and molecular genetics for the study of intracellular regulation of cholesterol metabolism has blossomed in recent years. This review lists all the Chinese hamster ovary cell mutants involved in cholesterol metabolism. In addition, it summarizes the characteristics of mutants involved in three different processes: (1) sequential cleavage of the membrane-bound sterol regulatory...
Topics
- Animals
- Biological Transport
- CCAAT-Enhancer-Binding Proteins
- CHO Cells
- Cholesterol
- Cholesterol Esters
- Cricetinae
- DNA-Binding Proteins
- Mutation
- Nuclear Proteins
- Sterol Regulatory Element Binding Protein 1
- Transcription Factors
