Article
Lessons from peroxisome-deficient Chinese hamster ovary (CHO) cell mutants.
Biochimica et biophysica acta - 1 Dec 2006
Fujiki Yukio, Okumoto Kanji, Kinoshita Naohiko, Ghaedi Kamran
Abstract excerpt
Cells with a genetic defect affecting a biological activity and/or a cell phenotype are generally called "cell mutants" and are a highly useful tool in genetic, biochemical, as well as cell biological research. To investigate peroxisome biogenesis and human peroxisome biogenesis disorders, more than a dozen complementation groups of Chinese hamster ovary (CHO) cell mutants defective in peroxisome assembly have...
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