Article
Replication-specific conversion of the Staphylococcus aureus pT181 initiator protein from an active homodimer to an inactive heterodimer.
The EMBO journal - 1 Nov 1994
Rasooly A, Wang P Z, Novick R P
Abstract excerpt
The Staphylococcus aureus rolling circle plasmid pT181 regulates its replication by controlling the synthesis of its initiator protein RepC. RepC is inactivated during pT181 replication by the addition of an oligodeoxynucleotide, giving rise to a new form, RepC*. We analyzed RepC and RepC* in fou...
Topics
- Bacterial Proteins
- Binding Sites
- DNA Replication
- DNA-Binding Proteins
- Genetic Complementation Test
- Molecular Weight
- Mutation
- Oligodeoxyribonucleotides
- Plasmids
- Protein Conformation
- Replication Origin
- Restriction Mapping
- Staphylococcus aureus