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Article

Replication-specific conversion of the Staphylococcus aureus pT181 initiator protein from an active homodimer to an inactive heterodimer.

The EMBO journal - 1 Nov 1994

Rasooly A, Wang P Z, Novick R P

Abstract excerpt

The Staphylococcus aureus rolling circle plasmid pT181 regulates its replication by controlling the synthesis of its initiator protein RepC. RepC is inactivated during pT181 replication by the addition of an oligodeoxynucleotide, giving rise to a new form, RepC*. We analyzed RepC and RepC* in four classes of mutants: plasmid copy number mutants, two classes of RepC mutants affecting different portions of the...

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Identifiers

PMID: 7957090
DOI: 10.1002/j.1460-2075.1994.tb06856.x
PMCID: PMC395475

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Source receipt: pubmed, retrieved 7 Sept 2026.

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Replication-specific conversion of the Staphylococcus aureus pT181 initiator protein from an active homodimer to an inactive heterodimer.PMID 7957090Read ↗

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