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Article

Prognostic significance of HER-2/neu gene amplification status by fluorescence in Situ hybridization of prostate carcinoma

1 Jun 1997

Abstract excerpt

BACKGROUND: HER-2/neu gene amplification, established as a prognostic factor in breast carcinoma and other cancers, has not been correlated with outcome in prostate carcinomas (PCs). METHODS: HER-2/neu gene amplification was determined by automated fluorescence in situ hybridization (FISH) using a unique sequence cosmid probe on 113 formalin fixed, paraffin embedded 4-microns tissue sections and the results...

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PMID: 9179063
DOI: 10.1002/(sici)1097-0142(19970601)79:11<2162::aid-cncr14>3.0.co;2-u

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