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Article

Prevalence and prognostic significance of TMPRSS2-ERG gene fusion in lymph node positive prostate cancers.

The Prostate - 1 Dec 2014

Fleischmann Achim, Saramäki Outi R, Zlobec Inti, Rotzer Diana, Genitsch Vera, Seiler Roland, Visakorpi Tapio, Thalmann George N

Abstract excerpt

BACKGROUND: TMPRSS2-ERG gene fusion is the most frequent genetic alteration in prostate cancer. However, information about its distribution in lymph node positive prostate cancers and the prognostic significance in these advanced tumors is unknown. METHODS: Gene fusion status was determined by fluorescence in situ hybridization on a tissue-microarray constructed from 119 hormone-naïve nodal positive, surgically...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25252136
DOI: 10.1002/pros.22882

Genes

ERG
TMPRSS2

Provenance

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Prevalence and prognostic significance of TMPRSS2-ERG gene fusion in lymph node positive prostate cancers.PMID 25252136Read ↗

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<i>TMPRSS2</i> : <i>ERG</i> Fusion Identifies a Subgroup of Prostate Cancers with a Favorable PrognosisSemantic proximity Read ↗

Expression of the TMPRSS2:ERG fusion gene predicts cancer recurrence after surgery for localised prostate cancerSemantic proximity Read ↗

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