HLA-DR antigens associated with major genetic risk for late-onset Alzheimer's disease.

doi:10.1097/00001756-199704140-00028

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Article

HLA-DR antigens associated with major genetic risk for late-onset Alzheimer's disease.

Neuroreport - 14 Apr 1997

Curran M, Middleton D, Edwardson J, Perry R, McKeith I, Morris C, Neill D

Abstract excerpt

Hla-dr antigen types were determined from DNA isolated from post-mortem brain tissue of age-matched groups of 78 patients with pathologically confirmed late-onset Alzheimer's disease (AD) and 50 controls. The results suggest that for individuals with no apolipoprotein E epsilon 4 alleles the pres...

Topics

Age of Onset
Aged
Aged, 80 and over
Alleles
Alzheimer Disease
Apolipoproteins E
Case-Control Studies
Female
HLA-DR Antigens
Humans
Male
Risk Factors

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