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Article

HLA-DR4 influences glial activity in Alzheimer's disease hippocampus.

Journal of the neurological sciences - 26 Nov 1998

Aisen P S, Luddy A, Durner M, Reinhard J F, Pasinetti G M

Abstract excerpt

The importance of inflammatory/immune mechanisms in Alzheimer's disease is supported by evidence that the human leukocyte antigen (HLA)-DR genotype influences risk of the disease, with a protective effect associated with the HLA-DR4 allele. We investigated the influence of the HLA-DR4 allele on g...

Topics

Alleles
Alzheimer Disease
Glial Fibrillary Acidic Protein
HLA-DR4 Antigen
Hippocampus
Humans
Neuroglia

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 9879683
DOI: 10.1016/s0022-510x(98)00268-8

Genes

GFAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9879683-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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