Article
Association between HLA-A alleles and Alzheimer's disease in a southern Chinese community.
Dementia and geriatric cognitive disorders - 1 Jan 2008
Ma Suk Ling, Tang Nelson Leung Sang, Tam Cindy Woon Chi, Lui Victor Wing Cheong, Suen Eddie Wai Chui, Chiu Helen Fung Kum, Lam Linda Chiu Wa
Abstract excerpt
BACKGROUND/AIM: HLA-A is a locus of the major histocompatibility complex situated on chromosome 6p21.3. Several genome-wide linkage analyses suggested that a putative locus predisposition for Alzheimer's disease (AD) is found on chromosome 6p21. In this study, we investigated the association between HLA-A alleles and AD in a Chinese community. METHODS: Fine genotyping of 160 Chinese AD and 167 age-matched...
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