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Article

Risk for Alzheimer's disease in older late-onset cases is associated with HLA-DRB1*03.

Neuroscience letters - 12 Nov 1999

Neill D, Curran M D, Middleton D, Mawhinney H, Edwardson J A, McKeith I, Ballard C, Morris C, Ince P, Jaros E, Perry R

Abstract excerpt

The allele frequency of the HLA-DRB1 gene was compared between groups of 48 clinically diagnosed elderly Alzheimer's disease (AD) cases and 44 pathologically confirmed elderly control cases. Specific primers were used to PCR amplify the highly polymorphic second exon of HLA-DRB1 using DNA extracted from blood samples or frozen brain tissue. The allele type was identified using sequence specific oligonucleotide...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 10568518
DOI: 10.1016/s0304-3940(99)00761-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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