Article
A role for phosphorylation by casein kinase II in modulating Antennapedia activity in Drosophila.
Genes & development - 15 May 1997
Jaffe L, Ryoo H D, Mann R S
Abstract excerpt
We present evidence that the in vivo activity of the HOX protein Antennapedia (ANTP) is modified because of phosphorylation by the serine/threonine kinase casein kinase II (CKII). Using an in vivo assay a form of ANTP that has alanine substitutions at its CKII target sites has, in addition to wil...
Topics
- Amino Acid Sequence
- Animals
- Antennapedia Homeodomain Protein
- Casein Kinase II
- DNA
- DNA-Binding Proteins
- Drosophila Proteins
- Drosophila melanogaster
- Genes, Homeobox
- Genetic Markers
- Homeodomain Proteins
- Molecular Sequence Data
- Nuclear Proteins
- Phenotype
- Phosphorylation
- Protein Binding
- Protein Serine-Threonine Kinases
- Transcription Factors