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Article

Axin-dependent phosphorylation of the adenomatous polyposis coli protein mediated by casein kinase 1epsilon.

The Journal of biological chemistry - 19 Oct 2001

Rubinfeld B, Tice D A, Polakis P

Abstract excerpt

Axin and the adenomatous polyposis coli protein (APC) interact to down-regulate the proto-oncogene beta-catenin. We show that transposition of an axin-binding site can confer beta-catenin regulatory activity to a fragment of APC normally lacking this activity. The fragment containing the axin-bin...

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Source

Identifiers

PMID: 11487578
DOI: 10.1074/jbc.M105148200

Genes

APC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-11487578-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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Axin-dependent phosphorylation of the adenomatous polyposis coli protein mediated by casein kinase 1epsilon.PMID 11487578Read ↗

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