Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Eukaryotic release factor 1 (eRF1) abolishes readthrough and competes with suppressor tRNAs at all three termination codons in messenger RNA

1 Jun 1997

Abstract excerpt

It is known from experiments with bacteria and eukaryotic viruses that readthrough of termination codons located within the open reading frame (ORF) of mRNAs depends on the availability of suppressor tRNA(s) and the efficiency of termination in cells. Consequently, the yield of readthrough products can be used as a measure of the activity of polypeptide chain release factor(s) (RF), key components of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to RNA and protein synthesis mechanisms
Share to RNA modifications and cancer
Share to Viral Infections and Immunology Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 9171074
DOI: 10.1093/nar/25.12.2254

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Eukaryotic release factor 1 (eRF1) abolishes readthrough and competes with suppressor tRNAs at all three termination codons in messenger RNAPMID 9171074Read ↗

Antizyme frameshifting as a functional probe of eukaryotic translational termination.Semantic proximity Read ↗

Translation termination in Arabidopsis thaliana: characterisation of three versions of release factor 1.Semantic proximity Read ↗

Transcriptome-wide investigation of stop codon readthrough in <i>Saccharomyces cerevisiae</i>Semantic proximity Read ↗

Leaky termination at premature stop codons antagonizes nonsense-mediated mRNA decay in S. cerevisiae.Semantic proximity Read ↗

Two-step model of stop codon recognition by eukaryotic release factor eRF1.Semantic proximity Read ↗

Terminating eukaryote translation: domain 1 of release factor eRF1 functions in stop codon recognition.Semantic proximity Read ↗

Reverse transcriptase of Moloney murine leukemia virus binds to eukaryotic release factor 1 to modulate suppression of translational termination.Semantic proximity Read ↗

Drug-induced eRF1 degradation promotes readthrough and reveals a new branch of ribosome quality controlSemantic proximity Read ↗

GTP hydrolysis by eRF3 facilitates stop codon decoding during eukaryotic translation termination.Semantic proximity Read ↗

Modulation of Stop Codon Read-Through Efficiency and Its Effect on the Replication of Murine Leukemia VirusSemantic proximity Read ↗

Decoding accuracy in eRF1 mutants and its correlation with pleiotropic quantitative traits in yeast.Semantic proximity Read ↗

Molecular dissection of translation termination mechanism identifies two new critical regions in eRF1.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.