Article
c-kit Point mutation in patients with myeloproliferative disorders.
Leukemia & lymphoma - 1 Apr 1997
Kimura A, Nakata Y, Katoh O, Hyodo H
Abstract excerpt
Myeloproliferative disorders (MPD) constitute a group of hematopoietic neoplasms at the myeloid stem cell level. Myeloid stem cells and/or progenitor cells from MPD have been considered sensitive to hematopoietic growth factors, including erythropoietin, thrombopoietin and stem cell factor (SCF). SCF is a ligand for c-kit receptor with tyrosine kinase. We analysed the gene alteration of the c-kit extracellular...
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