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Article

Mutational analysis of the KIT gene in myelodysplastic syndrome (MDS) and MDS-derived leukemia.

Leukemia research - 1 Oct 2006

Lorenzo Felipe, Nishii Kazuhiro, Monma Fumihiko, Kuwagata Shogo, Usui Eiji, Shiku Hiroshi

Abstract excerpt

The progenitor cells of myelodysplastic syndrome (MDS) are thought to undergo a multistep process during their transformation into overt acute leukemia. In this study, the role of mutation of the KIT gene in the extracellular membrane, juxtamembrane and tyrosine kinase domains was investigated in 75 patients with MDS or MDS-derived leukemia (MDS-AML). Mutation was detected in 2 of 15 (13.3%) patients with...

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Source

Identifiers

PMID: 16533529
DOI: 10.1016/j.leukres.2006.02.008

Genes

KIT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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