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Article

Genetic analysis of serine biosynthesis and glucose repression in yeast.

Current genetics - 1 Apr 1992

Melcher K, Entian K D

Abstract excerpt

Serine and glycine biosynthesis in yeast proceed by two pathways: a "glycolytic" pathway, using 3-phosphoglycerate, and a "gluconeogenic" pathway, using glyoxylate. We used a mutation in the cat1 gene to abolish the glucose-repressible "gluconeogenic" pathway and re-isolated two mutants, ser1 and ser2, in the "glycolytic" pathway. The ser1 mutation corresponded to phosphoserine transaminase and ser2 to that of...

Topics

Base Sequence
Fructose-Bisphosphatase
Genes, Fungal
Gluconeogenesis
Glucose
Glycolysis
Molecular Sequence Data
Mutation
Saccharomyces cerevisiae
Serine
Tryptophan
Uracil

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Source

Identifiers

PMID: 1326413
DOI: 10.1007/BF00351686

Genes

FBP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1326413-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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