Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Low frequency of TEL/AML1 in adult acute lymphoblastic leukemia.

Cancer genetics and cytogenetics - 15 Oct 1997

Kwong Y L, Wong K F

Abstract excerpt

Translocation (12;21)(p13;q22) is a recently characterized aberration in acute lymphoblastic leukemia, and results in the fusion of the TEL and the AML1 genes. It is the most common translocation in pediatric acute lymphoblastic leukemia (ALL), occurring in about one third of the cases. To determine the frequency of TEL/AML1 in adult ALL, we studied 4 cases of T lineage ALL and 26 cases of B lineage ALL. Only one...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Adolescent
Share to DNA-Binding Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Neoplasm Proteins

Share to Proto-Oncogene Proteins

Share to Repressor Proteins

Share to Transcription Factors

Source

Identifiers

PMID: 9332479
DOI: 10.1016/s0165-4608(96)00418-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Low frequency of TEL/AML1 in adult acute lymphoblastic leukemia.PMID 9332479Read ↗

Incidence of TEL/AML1 Fusion Gene Analyzed Consecutively in Children With Acute Lymphoblastic Leukemia in RelapseSemantic proximity Read ↗

Incidence and Clinical Relevance of TEL/AML1 Fusion Genes in Children With Acute Lymphoblastic Leukemia Enrolled in the German and Italian Multicenter Therapy TrialsSemantic proximity Read ↗

Low frequency of the TEL/AML1 fusion gene in acute lymphoblastic leukaemia in SpainSemantic proximity Read ↗

Occurrence of TEL-AML1 fusion resulting from (12;21) translocation in human early B-lineage leukemia cell lines.Semantic proximity Read ↗

The t(12;21) of acute lymphoblastic leukemia results in a tel-AML1 gene fusionSemantic proximity Read ↗

The 12;21 translocation involving TEL and deletion of the other TEL allele: two frequently associated alterations found in childhood acute lymphoblastic leukemia.Semantic proximity Read ↗

Amplification of AML1 gene is present in childhood acute lymphoblastic leukemia but not in adult, and is not associated with AML1 gene mutation.Semantic proximity Read ↗

TEL-AML1 translocations with TEL and CDKN2 inactivation in acute lymphoblastic leukemia cell linesSemantic proximity Read ↗

Outcome and lineage involvement in t(12;21) childhood acute lymphoblastic leukaemia.Semantic proximity Read ↗

TEL/AML-1 dimerizes and is associated with a favorable outcome in childhood acute lymphoblastic leukemiaSemantic proximity Read ↗

TEL/AML-1 dimerizes and is associated with a favorable outcome in childhood acute lymphoblastic leukemiaSemantic proximity Read ↗

Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.