Tracking the Evolutionary Origin of the Methicillin Resistance Gene: Cloning and Sequencing of a Homologue of <i>mecA</i> from a Methicillin Susceptible Strain of <i>Staphylococcus sciuri</i>

Abstract excerpt

The gene mecA, a central genetic determinant of methicillin resistance in Staphylococcus aureus and coagulase-negative staphylococci of human origin, has an unknown extra species origin in these human pathogens. After screening isolates representing over 15 different species within the genus Staphylococcus we could identify only one--S. sciuri--in which each of over 150 independent isolates showed positive...

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