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Evolutionary Models of the Emergence ofMethicillin-Resistant <i>Staphylococcusaureus</i>

24 Nov 2003

Abstract excerpt

Five major lineages of methicillin-resistant Staphylococcus aureus (MRSA) have evolved since the introduction of methicillin for the treatment of infections caused by penicillin-resistant S. aureus in 1959. The clones of these lineages are responsible for the vast majority of hospital-acquired MRSA disease globally. We have constructed high-resolution evolutionary models for each lineage using a parsimony...

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PMID: 14638503
DOI: 10.1128/aac.47.12.3926-3934.2003

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