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Article

Changes in the hemagglutinin molecule of influenza type A (H3N2) virus associated with increased virulence for mice.

Archives of virology - 1 Jan 1997

Hartley C A, Reading P C, Ward A C, Anders E M

Abstract excerpt

The H3N2 influenza virus A/Philippines/82 (Phil82) and its bovine serum-resistant mutant, Phil82/BS, were used to investigate factors that influence virulence of influenza virus for mice. Phil82/BS, which lacks the high-mannose oligosaccharide at residue 165 of the hemagglutinin (HA) molecule, was found to replicate to a much higher titer in mouse lung than the parent Phil82, and had acquired lethality for mice....

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Source

Identifiers

PMID: 9155874
DOI: 10.1007/s007050050060

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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