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Article

The herpes simplex virus type 1 2.0-kilobase latency-associated transcript is a stable intron which branches at a guanosine

1 Jun 1997

Abstract excerpt

We have used a minigene construct of the herpes simplex virus type 1 (HSV-1) latency-associated transcript (LAT) gene to analyze its transcripts in transient transfection assays. A 2.8-kb fragment of the approximately 8.5-kb LAT gene encompassing the 2.0-kb LAT was cloned into a eukaryotic expression vector downstream of the cytomegalovirus immediate-early gene promoter. Northern hybridization of RNA isolated...

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PMID: 9151806
DOI: 10.1128/jvi.71.6.4199-4208.1997

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The herpes simplex virus type 1 2.0-kilobase latency-associated transcript is a stable intron which branches at a guanosinePMID 9151806Read ↗

Herpes simplex virus latency-associated transcript is a stable intron.Semantic proximity Read ↗

The 2-kilobase intron of the herpes simplex virus type 1 latency-associated transcript has a half-life of approximately 24 hours in SY5Y and COS-1 cells.Semantic proximity Read ↗

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Atypical splicing of the latency-associated transcripts of herpes simplex type 1.Semantic proximity Read ↗

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A novel herpes simplex virus type 1 transcript (AL-RNA) antisense to the 5' end of the latency-associated transcript produces a protein in infected rabbits.Semantic proximity Read ↗

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