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Article

A novel herpes simplex virus type 1 transcript (AL-RNA) antisense to the 5' end of the latency-associated transcript produces a protein in infected rabbits.

Journal of virology - 1 Aug 2002

Perng Guey-Chuen, Maguen Barak, Jin Ling, Mott Kevin R, Kurylo John, BenMohamed Lbachir, Yukht Ada, Osorio Nelson, Nesburn Anthony B, Henderson Gail, Inman Melissa, Jones Clinton, Wechsler Steven L

Abstract excerpt

Following primary ocular infection, herpes simplex virus type 1 (HSV-1) establishes a lifelong latent infection in sensory neurons of the trigeminal ganglia. Latency-associated transcript (LAT), the only known viral gene abundantly transcribed during HSV-1 neuronal latency, is required for high levels of reactivation. Recently we showed that three different mutants that do not alter the LAT promoter but contain...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 12134005
DOI: 10.1128/jvi.76.16.8003-8010.2002
PMCID: PMC155148

Genes

LAT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A novel herpes simplex virus type 1 transcript (AL-RNA) antisense to the 5' end of the latency-associated transcript produces a protein in infected rabbits.PMID 12134005Read ↗

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