Article
Association of the angiotensinogen gene to serum angiotensinogen in blacks and whites.
Hypertension (Dallas, Tex. : 1979) - 1 May 1997
Bloem L J, Foroud T M, Ambrosius W T, Hanna M P, Tewksbury D A, Pratt J H
Abstract excerpt
A variant of the angiotensinogen gene (AGT) that encodes for threonine at codon 235 (T235) has been associated with a higher serum angiotensinogen concentration and with hypertension in white subjects. The frequency of T235 is about two times higher in blacks than whites, suggesting that AGT may contribute to the susceptibility to hypertension in blacks more than it does in whites. However, an association of T235...
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