The serum angiotensinogen concentration and variants of the angiotensinogen gene in white and black children.

doi:10.1172/JCI117803

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Article

The serum angiotensinogen concentration and variants of the angiotensinogen gene in white and black children.

The Journal of clinical investigation - 1 Mar 1995

Bloem L J, Manatunga A K, Tewksbury D A, Pratt J H

Abstract excerpt

The T235 allele of the angiotensinogen gene (AGT) has been associated with hypertension. Blood pressure increases faster over time in black children than in white children, and in adults hypertension is more prevalent in blacks. We sought evidence for a role for angiotensinogen to contribute to racial differences in blood pressure in a study of 148 white and 62 black normotensive children (mean age, 14.8 yr). The...

Topics

Adolescent
Adult
Aldosterone
Alleles
Angiotensinogen
Base Sequence
Black People
Blood Pressure Determination
Child
Female
Gene Frequency
Genetic Variation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Hypertension

Indiana

Longitudinal Studies

Male

Molecular Sequence Data

Source

Open in PubMed Open full text

Identifiers

PMID: 7883995
DOI: 10.1172/JCI117803
PMCID: PMC441426

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7883995-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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