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Article

The M235T polymorphism in the angiotensinogen gene is associated with the risk of malignant hypertension in white patients.

Journal of hypertension - 1 Nov 2007

van den Born Bert-Jan H, van Montfrans Gert A, Uitterlinden Andre G, Zwinderman Aeilko H, Koopmans Richard P

Abstract excerpt

BACKGROUND: Malignant hypertension can be considered an extreme phenotype of renin-mediated hypertension. Therefore, we compared the allelic frequencies of the angiotensinogen (AGT) M235T, angiotensin-converting enzyme insertion/deletion (ACE I/D) and angiotensin II-type I receptor (AT1R) A1166C polymorphisms in malignant hypertensive patients with hypertensive and normotensive controls. METHODS: A total of 101...

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Source

Identifiers

PMID: 17921816
DOI: 10.1097/HJH.0b013e3282efb213

Genes

AGT
ACE

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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