Article
Association of M235T variant of the angiotensinogen gene with familial hypertension of early onset.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Jan 1995
Schmidt S, Sharma A M, Zilch O, Beige J, Walla-Friedel M, Ganten D, Distler A, Ritz E
Abstract excerpt
A higher frequency of a variant of the angiotensinogen gene characterized by a transition in exon 2 causing a replacement of methionine by threonine (M235T) has recently been found in hypertensive individuals, but not all authors were able to confirm this observation. We examined (i) 219 patients with primary hypertension, (ii) 92 normotensive controls (spouses), and (iii) a sample of the general population...
Topics
- Adolescent
- Adult
- Age of Onset
- Aged
- Alleles
- Angiotensinogen
- Base Sequence
- Genotype
- Humans
- Hypertension
- Medical Records