Associations of candidate loci angiotensinogen and angiotensin-converting enzyme with severe hypertension: The NHLBI Family Heart Study.

doi:10.1016/s1047-2797(97)00155-5

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Article

Associations of candidate loci angiotensinogen and angiotensin-converting enzyme with severe hypertension: The NHLBI Family Heart Study.

Annals of epidemiology - 1 Jan 1997

Borecki I B, Province M A, Ludwig E H, Ellison R C, Folsom A R, Heiss G, Lalouel J M, Higgins M, Rao D C

Abstract excerpt

PURPOSE: In studies conducted in several different populations, the M235T substitution in the angiotensinogen (AGT) locus has been associated with hypertension. METHODS: A case-control study was initiated in an attempt to replicate this finding. Persons with hypertension, age- and sex-matched normotensive controls, and randomly sampled individuals were probands from the Family Heart Study of the National Heart,...

Topics

Angiotensinogen
Black People
Body Mass Index
Case-Control Studies
Coronary Disease
Female
Genotype
Humans
Hypertension
Logistic Models
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Massachusetts

Middle Aged

Minnesota

North Carolina

Peptidyl-Dipeptidase A

Polymorphism, Genetic

Risk Factors

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Open in PubMed

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PMID: 9034402
DOI: 10.1016/s1047-2797(97)00155-5

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