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Article

T helper cell-dependent, microbial superantigen-mediated B cell activation in vivo.

Autoimmunity - 1 Jan 1996

Tumang J R, Zhou J L, Gietl D, Crow M K, Elkon K B, Friedman S M

Abstract excerpt

We have utilized a severe combined immune-deficient (SCID) mouse adoptive transfer model to explore the in vivo immunostimulatory effects of bacterial superantigens (SAg). B cell reconstituted SCID recipients were treated with the Staphylococcus aureus-derived toxic shock syndrome toxin (TSST-1) alone or in conjunction with syngeneic L3T4+ TSST-1-reactive Th cells. Over several months of study, the repetitive...

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Identifiers

PMID: 9147583
DOI: 10.3109/08916939608994717

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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