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Article

Insulin gene/IDDM2 locus in Japanese type 1 diabetes: contribution of class I alleles and influence of class I subdivision in susceptibility to type 1 diabetes.

The Journal of clinical endocrinology and metabolism - 1 May 2007

Awata Takuya, Kawasaki Eiji, Ikegami Hiroshi, Kobayashi Tetsuro, Maruyama Taro, Nakanishi Koji, Shimada Akira, Iizuka Hiroyuki, Kurihara Susumu, Osaki Masataka, Uga Miho, Kawabata Yumiko, Tanaka Shoichiro, Kanazawa Yasuhiko, Katayama Shigehiro

Abstract excerpt

CONTEXT: It is suggested that insulin autoimmunity plays an important role in the development of type 1 diabetes in humans. However, the association between insulin gene (INS) region (IDDM2) and type 1 diabetes has been uncertain in Asians. OBJECTIVE: A multicenter collaboration study was conducted to clarify the role of the IDDM2 region in Japan. SUBJECTS AND METHODS: In total, 661 patients with type 1 diabetes...

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Identifiers

PMID: 17341563
DOI: 10.1210/jc.2006-2242

Genes

INS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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