Article
Correlation of resistance to the alkaloid lycorine with the degree of suppressiveness in petite mutants of Saccharomyces cerevisiae.
Current microbiology - 1 Jun 1997
Del Giudice A, Massardo D R, Manna F, Koltovaya N, Hartings H, Del Giudice L, Wolf K
Abstract excerpt
In previous papers (Del Giudice et al. Curr Genet 8:493-497, 1984; Massardo et al. Curr Genet 17:455-457, 1985) we have shown that strains of Saccharomyces cerevisiae that are devoid of mitochondrial DNA (rhoo) are resistant to the alkaloid lycorine isolated from Amaryllis plants, whereas strains containing mitochondrial DNA (rho-, mit-, or rho+) are sensitive to this drug. In addition, we were able to show that...
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