Article
Isolation and genetic study of triethyltin-resistant mutants of Saccharomyces cerevisiae.
Current genetics - 1 Jun 1990
Dupont C H, Rigoulet M, Aigle M, Guérin B
Abstract excerpt
Three mutants of Saccharomyces cerevisiae resistant to triethyltin (an inhibitor of mitochondrial ATPase) on non-fermentative media, and non-resistant to this drug on fermentative media, were isolated and named TTR1, TTR2 and TTR3. Apart from triethyltin resistance, these mutants show the following common characteristics: (1) Increased intracellular cytochrome c concentration. (2) Increased respiration rate. (3)...
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