Article
In vivo analysis of mtDNA replication defects in yeast.
Methods (San Diego, Calif.) - 1 Aug 2010
Baruffini Enrico, Ferrero Iliana, Foury Françoise
Abstract excerpt
The yeast Saccharomyces cerevisiae has the capacity to survive large deletions or total loss of mtDNA (petite mutants), and thus in the last few years it has been used as a model system to study defects in mitochondrial DNA (mtDNA) maintenance produced by mutations in genes involved in mtDNA repl...
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