Article
The temperature sensitivity of Bacillus subtilis DB1005 is due to insufficient activity, rather than insufficient concentration, of the mutant delta A factor.
Microbiology (Reading, England) - 1 Apr 1997
Chang Ban-Yang, Liao Chao-Tsai, Wen Yu-Der, Wang Wen-Horng
Abstract excerpt
The delta A factor of Bacillus subtilis DB1005 contains two amino acid substitutions (I198A and I202A) in the promoter-10 binding region. It has been confirmed that this delta factor is responsible for the temperature sensitivity of B. subtilis DB1005. An investigation was conducted into how the mutant delta A could cause temperature-sensitive (Ts) cell growth by analysing its structural stability, cellular...
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