Article
Angiotensin-converting enzyme gene I/D polymorphism in malignant hypertension.
Blood pressure - 1 Jan 2000
Stefansson B, Ricksten A, Rymo L, Aurell M, Herlitz H
Abstract excerpt
BACKGROUND: The mechanism of the rapid transition of a stable benign hypertensive disease to a severe and devastating malignant hypertension is not fully understood. However, the renin angiotensin system, which is highly activated in malignant hypertension, is established as an important pathogenetic factor in different cardiovascular and renal diseases. Over the last decade, a polymorphism in genes regulating...
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