Article
The angiotensin I-converting enzyme gene insertion/deletion polymorphism is linked to early gastric cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Dec 2005
Ebert Matthias P A, Lendeckel Uwe, Westphal Sabine, Dierkes Jutta, Glas Jürgen, Folwaczny Christian, Roessner Albert, Stolte Manfred, Malfertheiner Peter, Röcken Christoph
Abstract excerpt
The insertion/deletion polymorphism of the angiotensin I-converting enzyme (ACE) gene has recently been linked to the pathogenesis and progression of human cancers. Using genomic DNA from 88 patients with early gastric cancer confined either to mucosa (pT(1a)) or submucosa (pT(1b)), we assessed the insertion (I) and deletion (D) polymorphism by PCR analysis and compared it with a large noncancer control...
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