Article
Interaction between the angiotensin-converting enzyme gene insertion/deletion polymorphism and obstructive sleep apnoea as a mechanism for hypertension.
Journal of hypertension - 1 Apr 2007
Boström Kristina Bengtsson, Hedner Jan, Melander Olle, Grote Ludger, Gullberg Bo, Råstam Lennart, Groop Leif, Lindblad Ulf
Abstract excerpt
OBJECTIVE: Obstructive sleep apnoea (OSA) confers a risk of hypertension and cardiovascular complications. Both the renin-angiotensin-aldosterone system and OSA are important determinants of blood pressure, but it is not fully known how they interact. The aim of this study was to explore the interaction between the angiotensin-converting enzyme (ACE) gene insertion/deletion (I/D) polymorphism and OSA in the...
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