Article
Generation of a radial-like glial cell line.
Journal of neurobiology - 5 Nov 1998
Friedlander D R, Brittis P A, Sakurai T, Shif B, Wirchansky W, Fishell G, Grumet M
Abstract excerpt
Rat C6 glioma is a cell line that has been used extensively as a model of astroglia. Although this cell line retains many of the properties of developing glia, it does not resemble morphologically the specialized form of glia found embryonically, the radial glia. In experiments designed to study a mutant form of receptor protein tyrosine phosphatase beta, we isolated a subclone of C6 called C6-R which, like...
Topics
- Animals
- Cell Movement
- Cell Survival
- Cerebellum
- Clone Cells
- Glioma
- Neuroglia
- Phenotype
- Rats
- Tumor Cells, Cultured
