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Article

Evidence that the Dictyostelium Dd-STATa protein is a repressor that regulates commitment to stalk cell differentiation and is also required for efficient chemotaxis.

Development (Cambridge, England) - 1 Aug 1999

Mohanty S, Jermyn K A, Early A, Kawata T, Aubry L, Ceccarelli A, Schaap P, Williams J G, Firtel R A

Abstract excerpt

Dd-STATa is a structural and functional homologue of the metazoan STAT (Signal Transducer and Activator of Transcription) proteins. We show that Dd-STATa null cells exhibit several distinct developmental phenotypes. The aggregation of Dd-STATa null cells is delayed and they chemotax slowly to a cyclic AMP source, suggesting a role for Dd-STATa in these early processes. In Dd-STATa null strains, slug-like...

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PMID: 10393118
DOI: 10.1242/dev.126.15.3391

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Research trail→

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Evidence that the Dictyostelium Dd-STATa protein is a repressor that regulates commitment to stalk cell differentiation and is also required for efficient chemotaxis.PMID 10393118Read ↗

Evidence that the Dictyostelium STAT protein Dd-STATa plays a role in the differentiation of inner basal disc cells and identification of a promoter element essential for expression in these cells.Semantic proximity Read ↗

Identification of new modes of Dd-STATa regulation of gene expression in Dictyostelium by in situ hybridisation.Semantic proximity Read ↗

Developmentally and spatially regulated activation of a Dictyostelium STAT protein by a serpentine receptor.Semantic proximity Read ↗

Role of an expansin-like molecule in Dictyostelium morphogenesis and regulation of its gene expression by the signal transducer and activator of transcription protein Dd-STATa.Semantic proximity Read ↗

A Dictyostelium SH2 adaptor protein required for correct DIF-1 signaling and pattern formation.Semantic proximity Read ↗

A new Dictyostelium prestalk cell sub-type.Semantic proximity Read ↗

Cell type specificity of a diffusible inducer is determined by a GATA family transcription factor.Semantic proximity Read ↗

Characterization of a Dictyostelium factor that acts synergistically with DIF to induce terminal stalk cell differentiation.Semantic proximity Read ↗

Dd-STATb, a Dictyostelium STAT protein with a highly aberrant SH2 domain, functions as a regulator of gene expression during growth and early development.Semantic proximity Read ↗

Cell differentiation and patterning in Dictyostelium.Semantic proximity Read ↗

The phosphorylated C-terminus of cAR1 plays a role in cell-type-specific gene expression and STATa tyrosine phosphorylation.Semantic proximity Read ↗

Expression of zinc transporter family genes in Dictyostelium.Semantic proximity Read ↗

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