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Article

Differentiation of the shutoff of protein synthesis by virion host shutoff and mutant gamma (1)34.5 genes of herpes simplex virus 1.

Virology - 3 Mar 1997

Poon A P, Roizman B

Abstract excerpt

vhs protein is the product of the UL41 open reading frame of herpes simplex virus 1. The protein, made late in infection, is packaged into virions and, in newly infected cells, shuts off host protein synthesis by degrading mRNA. gamma (1)34.5 gene encodes a protein which precludes total shutoff o...

Topics

Animals
Cell Line
Chlorocebus aethiops
Genes, Viral
Herpesvirus 1, Human
Humans
Mutagenesis, Insertional
Mutation
Protein Biosynthesis
Rabbits
Ribonucleases
Tumor Cells, Cultured

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Vero Cells

Viral Proteins

Virion

Source

Identifiers

PMID: 9123882
DOI: 10.1006/viro.1996.8425

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9123882-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Differentiation of the shutoff of protein synthesis by virion host shutoff and mutant gamma (1)34.5 genes of herpes simplex virus 1.PMID 9123882Read ↗

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