Article
HIV-1 Env glycoproteins from two series of primary isolates: replication phenotype and immunogenicity.
Virology - 3 Mar 1997
Mustafa F, Richmond J F, Fernandez-Larsson R, Lu S, Fredriksson R, Fenyö E M, O'Connell M, Johnson E, Weng J, Santoro J C, Robinson H L
Abstract excerpt
Seven envelope regions from two series of patient isolates have been molecularly cloned and analyzed for replication phenotypes and immunogenicity. Growth potential was analyzed for env sequences substituted into an HIV-1-NL4-3 backbone (NL4-3/env recombinants). Immunogenicity studies were conducted on secreted monomeric (gp120) and oligomeric (gp140) forms of the Envs using Env-expressing plasmid DNAs for...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
