Article
DNA-binding specificity of Mcm1: operator mutations that alter DNA-bending and transcriptional activities by a MADS box protein.
Molecular and cellular biology - 1 Apr 1997
Acton T B, Zhong H, Vershon A K
Abstract excerpt
The yeast Mcm1 protein is a member of the MADS box family of transcriptional regulatory factors, a class of DNA-binding proteins found in such diverse organisms as yeast, plants, flies, and humans. To explore the protein-DNA interactions of Mcm1 in vivo and in vitro, we have introduced an extensi...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Binding Sites
- DNA, Fungal
- DNA-Binding Proteins
- Fungal Proteins
- Humans
- Minichromosome Maintenance 1 Protein
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Mutation
- Nucleic Acid Conformation
- Operator Regions, Genetic
- Protein Conformation
- Saccharomyces cerevisiae
- Transcription Factors
- Transcription, Genetic