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Article

DNA binding specificity determinants in MADS-box transcription factors.

Molecular and cellular biology - 1 Aug 1995

Nurrish S J, Treisman R

Abstract excerpt

The MADS box is a conserved sequence motif found in the DNA binding domain of a family of transcription factors which possess related but distinct DNA binding specificities. We investigated the basis of differential sequence recognition by the MADS-box proteins serum response factor (SRF), MCM1, and MEF2A, using chimeric proteins and site-directed mutants in conjunction with gel mobility shift and binding site...

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Identifiers

PMID: 7623803
DOI: 10.1128/MCB.15.8.4076
PMCID: PMC230646

Genes

SRF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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