Article
DNA binding specificity determinants in MADS-box transcription factors.
Molecular and cellular biology - 1 Aug 1995
Nurrish S J, Treisman R
Abstract excerpt
The MADS box is a conserved sequence motif found in the DNA binding domain of a family of transcription factors which possess related but distinct DNA binding specificities. We investigated the basis of differential sequence recognition by the MADS-box proteins serum response factor (SRF), MCM1,...
Topics
- Amino Acid Sequence
- Base Sequence
- Binding Sites
- Consensus Sequence
- DNA
- DNA Mutational Analysis
- DNA-Binding Proteins
- Genetic Variation
- MEF2 Transcription Factors
- Minichromosome Maintenance 1 Protein
- Models, Genetic
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Myogenic Regulatory Factors
- Nuclear Proteins
- Oligodeoxyribonucleotides
- Recombinant Fusion Proteins
- Selection, Genetic