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Article

Identification of cellular factors that recognize UV-damaged DNA in Drosophila melanogaster.

Mutation research - 1 Jan 1992

Todo T, Ryo H

Abstract excerpt

Using a gel electrophoresis DNA band-shift assay, we have identified 2 DNA-binding protein complexes in wild-type Drosophila embryonic cells which have high affinity for UV-irradiated, double-stranded DNA. Screening of Drosophila mutants deficient in DNA repair led to the identification of 5 mutants which lacked either one of the 2 protein complexes. Four excision repair-deficient mutants (mus-201, phr, mus-308...

Topics

Animals
Base Sequence
Chromatography, Agarose
DNA
DNA Damage
DNA Repair
DNA-Binding Proteins
Drosophila melanogaster
Molecular Sequence Data
Mutation
Ultraviolet Rays

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 1376438
DOI: 10.1016/0921-8777(92)90052-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1376438-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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