Article
Identification of cellular factors that recognize UV-damaged DNA in Drosophila melanogaster.
Mutation research - 1 Jan 1992
Todo T, Ryo H
Abstract excerpt
Using a gel electrophoresis DNA band-shift assay, we have identified 2 DNA-binding protein complexes in wild-type Drosophila embryonic cells which have high affinity for UV-irradiated, double-stranded DNA. Screening of Drosophila mutants deficient in DNA repair led to the identification of 5 mutants which lacked either one of the 2 protein complexes. Four excision repair-deficient mutants (mus-201, phr, mus-308...
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